Novak Djokovic can win with a -4.5 handicap. He is one of the strongest tennis players with high consistency and precision in his shots. His strong serve will help him secure breaks and create a lead. He is experienced and confidently plays against lower-level opponents, controlling the rallies. A possible match scenario: two sets with a score around 6-3 or 6-2, which would comfortably cover the handicap. Therefore, betting on Djokovic to win with a -4.5 handicap seems reasonable.
